Clinical and Roentgenological Study on Colo-rectal Diseases with Fine Ulcerative Lesions

Ulcerative lesions on the extremities with black eschar

Case: A 47-year-old Iranian man presented with a 3-month history of painful extremities lesions. The lesions began with an erythematous papule that progressively enlarged and ulcerated. His left calf was the first site of involvement. At the time we visited him, there were necrotic painful violaceous skin ulcers with a symmetrical distribution involving lower parts of distal limbs and his...

Meat and colo-rectal cancer.

In early epidemiological studies of diet and cancer the stress was on the search for causal factors. Population (ecological) studies tended to show a strong correlation between meat intake, particularly red meat, and the risk of colo-rectal cancer. They also tended to show meat to be strongly inversely correlated with cancers of the stomach and oesophagus and liver. Early case-control studies t...

Bioengineering of Colo-Rectal Tissue

Cruciferous vegetables and colo-rectal cancer.

Cruciferous vegetables have been studied extensively for their chemoprotective effects. Although they contain many bioactive compounds, the anti-carcinogenic actions of cruciferous vegetables are commonly attributed to their content of glucosinolates. Glucosinolates are relatively biologically inert but can be hydrolysed to a range of bioactive compounds such as isothiocyanates (ITC) and indole...

Folate, DNA stability and colo-rectal neoplasia.

Lower levels of dietary folate are associated with the development of epithelial cell tumours in man, particularly colo-rectal cancer. In the majority of epidemiological studies blood folate or reported folate intake have been shown to be inversely related to colo-rectal cancer risk. Folate, via its pivotal role in C1 metabolism, is crucial both for DNA synthesis and repair, and for DNA methyla...